The role of gut bacteria in heart and metabolic diseases
Gut Microbiota and Cardiometabolic Diseases
This study is looking at how the bacteria in our gut can affect heart health and metabolism, and it's for anyone interested in understanding how these tiny organisms might help improve conditions like heart disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10653038 on NIH RePORTER |
What this research studies
This research investigates how gut microbiota influences cardiovascular and metabolic diseases. It aims to understand the mechanisms by which gut bacteria produce metabolites that affect heart health and metabolic functions. The study involves analyzing gut microbial pathways and their impact on conditions like atherosclerosis through both animal models and human participants. By exploring these connections, the research seeks to uncover new therapeutic targets for improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals with cardiovascular diseases or metabolic disorders who are interested in understanding the role of gut health in their conditions.
Not a fit: Patients without cardiovascular or metabolic diseases may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart health and metabolic conditions by targeting gut microbiota.
How similar studies have performed: Other research has shown promising results in understanding the gut microbiome's role in health, indicating potential for success in this area.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Hazen, Stanley L — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Hazen, Stanley L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.