The NeuroSpan Bridge for Peripheral Nerve Repair
Official title: The Neurospan Bridge: A Device for Peripheral Nerve Repair
Funded at Auxilium Biotechnologies INC. · NIH-11184518 · Data updated 2026-11-12
A biomimetic, multi-channel nerve repair device designed to speed and guide nerve healing after injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Auxilium Biotechnologies INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | March 15, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,500,000 |
| NIH project number | 5U44NS128489-03 |
| Project ID | NIH-11184518 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with peripheral nerve injuries suitable for repair, including those with gaps that may benefit from a biomimetic scaffold.
✕Less likely to help
Patients with injuries not eligible for nerve grafts or those with injuries beyond the scope of the device may not benefit.
What this research studies
This project aims to finalize pre-clinical work, obtain FDA IDE clearance, and test a first-in-human feasibility study of a new nerve repair device. It builds on animal studies showing the device can outperform nerve autografts for longer gaps, with the goal of offering a practical option for patients with peripheral nerve injuries. If successful, it could streamline recovery, reduce donor-site morbidity, and provide a scalable treatment that can be translated across centers. The team combines experts in nerve injury, regeneration, neurosurgery, neurology, and bioengineering to advance toward a 510(k) submission.
Why it matters
Potential benefit: If successful, patients with peripheral nerve injuries could experience faster, more reliable nerve regeneration and a reduction in the need for donor-site harvesting.
How similar studies have gone: Prior animal studies showed superiority of the NeuroSpan Bridge over existing devices and autografts in relevant models.
Where this research is happening
-
Auxilium Biotechnologies INC.
San Diego, United States Active
Researchers
- Principal investigator: Koffler, Yacov — Auxilium Biotechnologies INC.
- Study coordinator: Koffler, Yacov
Related research
Other NIH-funded projects on the same topics.
-
NeuroSpan Bridge to repair damaged peripheral nerves
This project is trying an implantable scaffold called NeuroSpan to help people with peripheral nerve injuries regrow nerves and recover function.
-
A device designed to repair damaged peripheral nerves.
This study is testing a new device called the NeuroSpan Bridge that helps heal nerve injuries by guiding the growth of nerve fibers, and it's designed for people who have suffered from nerve damage.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.