A device designed to repair damaged peripheral nerves.
Official title: The Neurospan Bridge: A Device for Peripheral Nerve Repair
Funded at Auxilium Biotechnologies INC. · NIH-11009477 · Data updated 2026-11-12
This study is testing a new device called the NeuroSpan Bridge that helps heal nerve injuries by guiding the growth of nerve fibers, and it's designed for people who have suffered from nerve damage.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Auxilium Biotechnologies INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | March 15, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,500,000 |
| NIH project number | 4U44NS128489-02 |
| Project ID | NIH-11009477 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have sustained peripheral nerve injuries, particularly those with gaps in the nerve that require surgical intervention.
✕Less likely to help
Patients with nerve injuries that are not amenable to surgical repair or those with conditions unrelated to peripheral nerve damage may not benefit from this research.
What this research studies
This research focuses on developing the NeuroSpan Bridge, a biomimetic device that aids in the repair of peripheral nerve injuries. It utilizes a multi-channel scaffold to guide and accelerate the regeneration of nerve fibers, which is crucial for restoring function after nerve damage. The project includes extensive pre-clinical testing and aims to conduct a feasibility clinical study to evaluate its effectiveness in humans. By collaborating with experts in various fields, the research seeks to create a reliable and cost-effective solution for patients suffering from nerve injuries.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery outcomes for patients with peripheral nerve injuries.
How similar studies have gone: Previous research has shown promising results with similar biomimetic approaches in animal models, indicating potential for success in human applications.
Where this research is happening
-
Auxilium Biotechnologies INC.
San Diego, United States Active
Researchers
- Principal investigator: Koffler, Yacov — Auxilium Biotechnologies INC.
- Study coordinator: Koffler, Yacov
Related research
Other NIH-funded projects on the same topics.
-
NeuroSpan Bridge to repair damaged peripheral nerves
This project is trying an implantable scaffold called NeuroSpan to help people with peripheral nerve injuries regrow nerves and recover function.
-
The NeuroSpan Bridge for Peripheral Nerve Repair
A biomimetic, multi-channel nerve repair device designed to speed and guide nerve healing after injuries.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.