The impact of environmental pollutants on heart health in postmenopausal women
Circulating levels of Persistent Organic Pollutants and Subclinical Atherosclerosis progression in Postmenopausal women
This study is looking at how long-term exposure to certain harmful chemicals in the environment might affect heart health in postmenopausal women by checking changes in their blood and arteries over five years.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10897873 on NIH RePORTER |
What this research studies
This research investigates how exposure to persistent organic pollutants (POPs) affects the progression of subclinical atherosclerosis in postmenopausal women. By analyzing blood samples over a five-year period, the study aims to understand the long-term effects of these pollutants on cardiovascular health. Participants will be monitored for changes in carotid intima-media thickness, a key indicator of atherosclerosis. The research seeks to fill a gap in knowledge regarding the impact of environmental toxins on heart disease in this specific population.
Who could benefit from this research
Good fit: Ideal candidates for this research are postmenopausal women who may have been exposed to environmental pollutants.
Not a fit: Patients who are not postmenopausal or those without exposure to persistent organic pollutants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for cardiovascular disease in postmenopausal women.
How similar studies have performed: While there has been some success in similar studies abroad, this research focuses on a unique cohort in the US and aims to explore untested associations.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Karim, Roksana — University of Southern California
- Study coordinator: Karim, Roksana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.