The impact of early life stress on heart and metabolic health in teenagers

Early life stress and cardiometabolic health in adolescence

NIH-funded research University of Minnesota · NIH-10609454

This study looks at how stress from early childhood can affect heart and health in teenagers, especially focusing on kids adopted from orphanages compared to those raised by their biological families, to help us understand how early experiences shape long-term health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-10609454 on NIH RePORTER

What this research studies

This research investigates how stress experienced during early childhood affects heart and metabolic health in adolescents. It focuses on children adopted from orphanages into supportive homes, comparing their health outcomes to those of peers raised in their biological families. The study aims to identify critical periods when stress impacts health and to explore the biological mechanisms involved. By assessing cardiometabolic functioning in teenagers, the research seeks to understand long-term health risks associated with early life stress.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12-20 who were adopted from orphanages and are now living in well-resourced homes.

Not a fit: Patients who have not experienced significant early life stress or who are not within the specified age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cardiovascular and metabolic diseases in adolescents who have experienced early life stress.

How similar studies have performed: Previous research has shown that early life stress can significantly impact long-term health, indicating that this study builds on established findings rather than exploring a completely novel approach.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.