Texas TEX CTN: Advanced cancer therapy network
Official title: Texas EXperimental Cancer Therapeutics Network - TEX CTN
Funded at University of Tx Md Anderson Can Ctr · NIH-11497908 · Data updated 2026-11-12
A large cancer research network partners with multiple centers to test new targeted therapies in patients whose tumors have specific molecular features.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | March 14, 2014 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,519,430 |
| NIH project number | 3UM1CA186688-09S1 |
| Project ID | NIH-11497908 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with cancers whose tumors have identifiable molecular abnormalities and who are eligible for targeted therapy trials within the network.
✕Less likely to help
Patients without matched molecular targets or who are not eligible for the current trials may not benefit.
What this research studies
This NIH-funded UM1 program coordinates trials across Texas to rapidly evaluate new cancer drugs or combinations in molecularly profiled patients. It integrates early pharmacodynamic markers to understand how treatments work and to guide patient selection. The network also studies predictors of who responds or develops resistance, and it supports mentoring of junior investigators and staff. The project aims to generate clinically useful biomarkers, optimize trial designs, and advance translational cancer therapies.
Why it matters
Potential benefit: If successful, patients could receive more precisely matched therapies and contribute to knowledge that speeds approvals for effective treatments.
How similar studies have gone: Previous networks with molecular profiling in trials have shown promise in guiding therapy, though results vary by agent and tumor type.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Meric-Bernstam, Funda — University of Tx Md Anderson Can Ctr
- Study coordinator: Meric-Bernstam, Funda
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.