Testing message-based therapy for depression

Message-based psychotherapy and digital treatment sequences for depression

NIH-funded research Talkspace LLC · NIH-10701040

This study is looking at whether daily text-based therapy or traditional video chat therapy is better for helping people with depression feel better, and it’s for anyone interested in finding out which method might work best for them.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionTalkspace LLC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10701040 on NIH RePORTER

What this research studies

This research investigates the effectiveness of daily message-based psychotherapy (MBP) compared to traditional video-chat psychotherapy (VCP) for treating depression. It involves a pilot study to identify the best ways to keep participants engaged, followed by a randomized clinical trial to compare the two therapy methods. Participants will share information about their mood and daily activities, helping researchers understand which treatment works better and how to improve care for those who do not respond to initial therapies.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 18 and older who are experiencing symptoms of depression.

Not a fit: Patients who are not experiencing depression or who are currently receiving effective treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more accessible and effective treatment option for individuals suffering from depression.

How similar studies have performed: Previous research has shown promise in using digital platforms for therapy, suggesting that this approach could be effective.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental disordersMental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.