Testing genome editing tools and their effects in nonhuman primates
Official title: Genome Editing and Biological Effects Testing Component
Funded at University of California at Davis · NIH-10911367 · Data updated 2026-11-12
This study is looking at how well new gene-editing tools work and how safe they are by testing them on monkeys, with the hope that what we learn can help create better treatments for genetic diseases in people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $651,851 |
| NIH project number | 5U42OD035737-02 |
| Project ID | NIH-10911367 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals with genetic conditions that could be addressed through genome editing.
✕Less likely to help
Patients with conditions unrelated to genetic disorders or those who do not meet the age criteria may not receive any benefit from this research.
What this research studies
This research investigates the effectiveness and safety of genome editing technologies using nonhuman primates. It focuses on evaluating how well these editing tools work across different age groups and examines any biological effects, including potential inflammation and immune responses. By testing various delivery methods and editing tools, the research aims to enhance the translation of these technologies into potential treatments for human diseases. Patients may benefit from advancements in genome editing that could lead to new therapies for genetic conditions.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective genome editing therapies for human diseases.
How similar studies have gone: Previous research has shown promise in genome editing technologies, indicating potential for significant advancements in treatment options.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Segal, David J — University of California at Davis
- Study coordinator: Segal, David J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.