Testing a new skin patch for delivering flu medication.
Official title: Phase 1 Clinical Trial to Assess the Pharmacokinetics, Safety and Tolerance of a Zanamivir Transdermal System in Healthy Subjects
Funded at Tsrl, INC. · NIH-10929746 · Data updated 2026-11-12
This study is testing a new skin patch that delivers the flu medicine zanamivir, making it easier for people who struggle with inhalers, and healthy volunteers are needed to help see how well it works and if it's safe to use.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tsrl, INC. NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | July 10, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $292,746 |
| NIH project number | 1U44AI184201-01 |
| Project ID | NIH-10929746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are healthy adults who are willing to participate in a clinical trial and meet specific inclusion criteria.
✕Less likely to help
Patients with existing respiratory conditions or those who are not healthy adults may not benefit from this research.
What this research studies
This research investigates a new way to deliver the influenza medication zanamivir through a skin patch, which could be more effective for patients who have difficulty using inhalers. The study will assess how well the medication is absorbed through the skin, its safety, and how well patients tolerate it. By using a microarray-enabled transdermal delivery system, the goal is to provide a painless and efficient method for administering the drug, especially during flu outbreaks. Healthy volunteers will participate in this trial to help determine the patch's effectiveness.
Why it matters
Potential benefit: If successful, this research could provide a more accessible and effective treatment option for influenza, particularly for those unable to use traditional inhalers.
How similar studies have gone: Other research has shown promise in using transdermal delivery systems for various medications, indicating potential success for this novel approach.
Where this research is happening
-
Tsrl, INC.
Ann Arbor, United States Active
Researchers
- Principal investigator: Lipka, Elke — Tsrl, INC.
- Study coordinator: Lipka, Elke
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.