Targeting immune cells to treat autoimmune diseases
Official title: Johns Hopkins Autoimmunity Center of Excellence
Funded at Johns Hopkins University · NIH-10844862 · Data updated 2026-11-12
This study is looking at how certain immune cells affect autoimmune diseases like multiple sclerosis and myositis, and it aims to find new treatments that can help slow down or change the course of these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $81,875 |
| NIH project number | 1UM1AI181725-01 |
| Project ID | NIH-10844862 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals diagnosed with secondary progressive multiple sclerosis or active, autoantibody positive myositis.
✕Less likely to help
Patients with inclusion body myositis or those not diagnosed with the targeted autoimmune conditions may not benefit from this research.
What this research studies
The Johns Hopkins Autoimmunity Center of Excellence focuses on understanding how specific immune cell types contribute to autoimmune diseases and aims to develop targeted therapies to modify or halt disease progression. The research involves clinical projects that target effector-memory T cells and B cells in conditions like secondary progressive multiple sclerosis and myositis. By using innovative treatments and advanced assessments, the research seeks to identify and address the underlying immune mechanisms driving these diseases.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with autoimmune diseases, improving their quality of life and disease management.
How similar studies have gone: Previous research has shown promise in targeting immune cells for autoimmune diseases, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Paik, Julie Jisun — Johns Hopkins University
- Study coordinator: Paik, Julie Jisun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.