Targeting genetic changes in pancreatic cancer
Understanding and targeting mutant splicing factors in pancreatic cancer
This study is looking at how certain changes in genes related to splicing might help pancreatic cancer grow and spread, with the goal of creating new treatments that target these changes to help patients live longer and feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11062893 on NIH RePORTER |
What this research studies
This research investigates how specific mutations in splicing factors contribute to the development and progression of pancreatic cancer. By understanding these mutations, the research aims to develop targeted therapies that can more effectively treat this aggressive cancer. Patients may benefit from new treatment options that specifically address the underlying genetic changes in their tumors, potentially improving outcomes and survival rates.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic cancer, particularly those with mutations in splicing factors.
Not a fit: Patients with pancreatic cancer who do not have mutations in splicing factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, improving survival rates and quality of life for patients.
How similar studies have performed: Other research has shown promising results in targeting genetic mutations in various cancers, suggesting that this approach may also be effective for pancreatic cancer.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Escobar Hoyos, Luisa — Yale University
- Study coordinator: Escobar Hoyos, Luisa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.