Targeted treatment for blood clots using a specialized microgel
Targeted treatment of thrombotic occlusions using a dual-delivery microgel therapeutic
This study is testing a new treatment for blood clots that not only helps clear the clots quickly but also prevents scarring in the affected area, which can help keep your body working well afterward.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10903125 on NIH RePORTER |
What this research studies
This research focuses on developing a new treatment for blood clots that can cause serious health issues like heart attacks and deep vein thrombosis. It aims to quickly restore blood flow while also preventing scar tissue formation that can occur after a clot is resolved. The approach involves using a dual-delivery system that combines a drug to dissolve clots with another to inhibit fibrosis, which is the scarring process that can limit tissue function. Patients may benefit from this innovative treatment that addresses both immediate and long-term complications of thrombotic occlusions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing or at risk for thrombotic occlusions, such as those with a history of heart attacks, deep vein thrombosis, or pulmonary embolism.
Not a fit: Patients who do not have thrombotic occlusions or related vascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a groundbreaking treatment that not only clears blood clots but also prevents harmful scarring in affected tissues.
How similar studies have performed: While this approach is innovative, similar strategies targeting both clot resolution and fibrosis prevention have shown promise in preliminary studies.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Brown, Ashley Carson — North Carolina State University Raleigh
- Study coordinator: Brown, Ashley Carson
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.