Swine Somatic Cell Genome Editing Center
Official title: Swine Somatic Cell Gene Editing Testing Center
Funded at University of Missouri-Columbia · NIH-11393739 · Data updated 2026-11-12
A center that helps researchers work with edited pig cells and animals to study genome editing safely and efficiently, with the aim of advancing basic science and future clinical applications.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri-Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project start | September 12, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,328,901 |
| NIH project number | 5U42OD035738-04 |
| Project ID | NIH-11393739 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patients directly; however, future clinical benefits may arise from translational research using swine genome-editing models.
✕Less likely to help
People currently seeking immediate treatments may not participate in this program.
What this research studies
This NIH-funded center provides services to produce, import, cryopreserve, and supply swine models used in somatic cell genome editing research. It also evaluates how safe and effective genome-editing strategies are and explores when therapies might work best and for how long. The center coordinates communication, logistics, and regulatory reporting, while maintaining BSL-2 facilities and breeding colonies to support researchers. By testing new delivery methods and reagents, the center aims to accelerate both basic research and the translation of therapies toward clinic use. Researchers and institutions can collaborate through a structured framework that connects model production, testing, and translational potential.
Why it matters
Potential benefit: If successful, this center could speed the development of genome-edited therapies by providing robust swine models and safer, more effective delivery methods.
How similar studies have gone: Previous genome editing centers have shown that standardized swine models and testing can accelerate therapeutic development, though this project focuses on building and validating a specialized testing center.
Where this research is happening
-
University of Missouri-Columbia
Columbia, United States Active
Researchers
- Principal investigator: Green, Jonathan a — University of Missouri-Columbia
- Study coordinator: Green, Jonathan a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.