NIH-funded research NIH-funded research

Sustaining proven mental health lifestyle programs to cut heart risks

Official title: Dynamic Sustainment of Evidence-Based Health Promotion Interventions in Mental Health

Funded at Dartmouth-Hitchcock Clinic · NIH-11395586 · Data updated 2026-11-12

A long-term study to keep a proven lifestyle program (InSHAPE) helping adults with serious mental illness reduce heart disease risk while staying active in real-world mental health settings.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDartmouth-Hitchcock Clinic
NIH-funded
Lab location1 site (Lebanon, United States)
Project startSeptember 16, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$1,848,111
NIH project number4RF1MH133610-03
Project IDNIH-11395586 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21+ with serious and disabling mental illness who are receiving care in participating mental health organizations.

Less likely to help

Individuals without access to participating organizations may not directly benefit.

What this research studies

This project aims to keep an evidence-based lifestyle program running in mental health organizations so adults with serious mental illness can continue to benefit from healthier habits. Researchers will partner with community clinics to adapt and sustain InSHAPE beyond initial research funding, using real-world data and implementation methods. The emphasis is on long-term delivery, not just short-term outcomes, so people with SMI can maintain healthier weights and lower cardiovascular risk over time. Participants will see programs that are already shown to help and will be followed to understand what keeps them going in everyday practice.

Why it matters

Potential benefit: If successful, the program could help more adults with serious mental illness maintain healthier lifestyles and reduce early cardiovascular deaths.

How similar studies have gone: InSHAPE has shown health benefits in multiple trials and implementations, but long-term sustainment in real-world settings is not yet proven.

Where this research is happening

  • Dartmouth-Hitchcock Clinic
    Lebanon, United States
    Active

Researchers

  • Principal investigator: Aschbrenner, Kelly a — Dartmouth-Hitchcock Clinic
  • Study coordinator: Aschbrenner, Kelly a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.