Support Toolkit to Boost Cancer Clinical Trial Participation
Official title: The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
Funded at Ecog-Acrin Medical Research Foundation · NIH-11391063 · Data updated 2026-11-12
A multi-level program to help more cancer patients join NCI-supported clinical trials using a patient-friendly literacy tool and navigators.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ecog-Acrin Medical Research Foundation NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $629,017 |
| NIH project number | 5U01CA274996-05 |
| Project ID | NIH-11391063 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with cancer who are receiving care at ECOG-ACRIN-affiliated community oncology sites and are potential candidates for NCI-supported therapeutic trials.
✕Less likely to help
Patients not eligible for trials or not seeking trial participation may not benefit from this intervention.
What this research studies
This program aims to reduce barriers to joining cancer clinical trials by empowering patients, providers, and clinics with easy-to-use information and dedicated trial navigators. It will implement and test a toolkit that improves understanding of trials, guides referrals, and supports enrollment at community sites. By leveraging ECOG-ACRIN’s experience and network, the project seeks to increase access to cutting-edge treatments for diverse patient populations.
Why it matters
Potential benefit: If successful, more cancer patients could be referred to and enroll in trial treatments, expanding access to new therapies and precision medicine.
How similar studies have gone: Previous work in patient navigation and trial literacy has improved referrals and awareness, supporting potential success for this approach.
Where this research is happening
-
Ecog-Acrin Medical Research Foundation
Philadelphia, United States Active
Researchers
- Principal investigator: Simon, Melissa a. — Ecog-Acrin Medical Research Foundation
- Study coordinator: Simon, Melissa a.
Related research
Other NIH-funded projects on the same topics.
-
ECOG-ACRIN NCORP Research Base overview for cancer care and prevention
A national cancer research network is running patient-centered trials and biomarker work through community sites to improve prevention, early detection, treatment, and survivorship.
-
Biorepository for Cancer Biospecimens to Advance Cancer Care
A national cancer biorepository program will securely collect, store, and share labeled tissue, blood, and other biospecimens from cancer patients to help researchers develop better tests and treatments.
-
ECOG-ACRIN cancer clinical trials network
This program runs cancer clinical trials and prevention studies to expand treatment options and improve quality of life for people with cancer and cancer survivors.
-
ECOG-ACRIN Community Cancer Research Network
This program runs clinical trials and prevention projects to improve cancer care and quality of life for people treated in community clinics.
-
Member Site Core (cancer trials network core for biomarker-driven research)
A nationwide cancer trial network core is advancing biomarker-guided therapies by linking imaging, biology, and clinical trials to improve care for adults with cancer.
-
Clinical Trials Development Core for cancer patients
A nationwide cancer research program helps develop new treatments and imaging tools to improve care for adults with cancer.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.