NIH-funded research NIH-funded research

ECOG-ACRIN NCORP Research Base overview for cancer care and prevention

Official title: ECOG-ACRIN NCORP Research Base

Funded at Ecog-Acrin Medical Research Foundation · NIH-11621190 · Data updated 2026-11-12

A national cancer research network is running patient-centered trials and biomarker work through community sites to improve prevention, early detection, treatment, and survivorship.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEcog-Acrin Medical Research Foundation
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startAugust 1, 2014
Project endJuly 31, 2027
Funding year2026
Award (this year)$79,203
NIH project number3UG1CA189828-12S1
Project IDNIH-11621190 on NIH RePORTER

Who could benefit from this research

Could help

Adults and adolescents with or at risk for cancer who receive care in community oncology settings and participate in NCORP trials.

Less likely to help

Patients not enrolled in NCORP trials or without access to participating community sites may not directly benefit.

What this research studies

This grant supports the ECOG-ACRIN Cancer Research Group as an NCORP Research Base, connecting community providers with translational and clinical cancer studies. The program emphasizes precision oncology, immuno-oncology, reducing overdiagnosis and overtreatment, and the use of biomarker platforms to guide care. It includes trials that measure patient-reported outcomes to understand quality of life and symptom burden, as well as efforts to reduce treatment-related cardiotoxicity. The research spans prevention, early detection, treatment, and survivorship to improve outcomes in real-world clinical settings.

Why it matters

Potential benefit: If successful, patients may experience more personalized, less toxic cancer care and better support for quality of life during and after treatment.

How similar studies have gone: Previous NCORP trials have demonstrated the feasibility of community-based trials and meaningful patient-reported outcomes in guiding care.

Where this research is happening

  • Ecog-Acrin Medical Research Foundation
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Wagner, Lynne I. — Ecog-Acrin Medical Research Foundation
  • Study coordinator: Wagner, Lynne I.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.