Support program for patients and caregivers with advanced gynecologic and gastrointestinal cancers

BOLSTER: Strengthening Patient and Caregiver Supports in Advanced Gynecologic and Gastrointestinal Cancers - a Multi-Site Randomized Controlled Trial

NIH-funded research Dana-Farber Cancer Inst · NIH-11008925

This program pairs patients and their caregivers with a nurse, regular telehealth check-ins, and a symptom-tracking app to help manage severe symptoms and reduce hospital visits for people with advanced GI or gynecologic cancers.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11008925 on NIH RePORTER

What this research studies

You would be paired with a nurse who keeps in touch over time through scheduled telehealth visits. You'll use a mobile platform to report symptoms between visits so your care team can respond quickly. The program also gives tailored training for managing complex issues like drains, ostomies, or ascites and skills support for family caregivers. The trial randomizes patients across several cancer centers to compare this enhanced support with usual care.

Who could benefit from this research

Good fit: Adults with advanced gastrointestinal or gynecologic cancers who have complex symptoms (for example ascites, bowel obstruction, ostomies, or drains) and a willing family caregiver are the ideal candidates.

Not a fit: People with early-stage disease, no complex symptom-management needs, no available caregiver, or no access to telehealth or a smartphone may not gain benefit from this program.

Why it matters

Potential benefit: If successful, the program could improve quality of life, ease symptoms, and reduce burdensome hospital stays for patients while lowering caregiver strain.

How similar studies have performed: A prior pilot randomized trial showed BOLSTER was feasible and acceptable, but larger trials are needed to confirm clinical benefits.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced CancerCancer Cause
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.