Studying how cytokines signal in chronic diseases over time
Official title: Integrating Real-Time Multi-System Cytokine Signaling in Chronic Disease
Funded at City College of New York · NIH-11092104 · Data updated 2026-11-12
This study is exploring how certain proteins in the body, called cytokines, affect long-lasting health issues, using a special sensor that can be injected to check these proteins in real-time, which could help us understand and improve treatments for chronic inflammation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2021 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $392,500 |
| NIH project number | 5R35GM142833-05 |
| Project ID | NIH-11092104 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic diseases, particularly those with autoimmune conditions or chronic inflammatory disorders.
✕Less likely to help
Patients with acute conditions or those not experiencing chronic inflammation may not benefit from this research.
What this research studies
This research investigates the role of pro-inflammatory cytokines in chronic diseases by developing a novel fluorescent carbon nanosensor platform. The approach involves creating a minimally invasive injectable hydrogel that can detect multiple cytokines simultaneously in real-time. By using rodent models, the research aims to understand the timing and functionality of cytokine signaling during the transition from acute to chronic inflammation. This could lead to better insights into disease progression and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment of chronic diseases by providing real-time insights into inflammatory processes.
How similar studies have gone: While the approach of using nanosensors for cytokine detection is innovative, similar technologies have shown promise in other areas of biomedical research, indicating potential for success.
Where this research is happening
-
City College of New York
New York, United States Active
Researchers
- Principal investigator: Williams, Ryan Martin — City College of New York
- Study coordinator: Williams, Ryan Martin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.