Studying how cytokines signal in chronic diseases over time
Integrating Real-Time Multi-System Cytokine Signaling in Chronic Disease
This study is exploring how certain proteins in the body, called cytokines, affect long-lasting health issues, using a special sensor that can be injected to check these proteins in real-time, which could help us understand and improve treatments for chronic inflammation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11092104 on NIH RePORTER |
What this research studies
This research investigates the role of pro-inflammatory cytokines in chronic diseases by developing a novel fluorescent carbon nanosensor platform. The approach involves creating a minimally invasive injectable hydrogel that can detect multiple cytokines simultaneously in real-time. By using rodent models, the research aims to understand the timing and functionality of cytokine signaling during the transition from acute to chronic inflammation. This could lead to better insights into disease progression and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic diseases, particularly those with autoimmune conditions or chronic inflammatory disorders.
Not a fit: Patients with acute conditions or those not experiencing chronic inflammation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment of chronic diseases by providing real-time insights into inflammatory processes.
How similar studies have performed: While the approach of using nanosensors for cytokine detection is innovative, similar technologies have shown promise in other areas of biomedical research, indicating potential for success.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Williams, Ryan Martin — City College of New York
- Study coordinator: Williams, Ryan Martin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.