NIH-funded research R01 grant

STREAMS: streamlined counseling and medication support for adolescents with HIV

Official title: Streamlined Treatment and Evidence-based Adolescent counseling and Medication Support (STREAMS)

Funded at Graduate School of Public Health and Health Policy · NIH-11417983 · Data updated 2026-11-12

A new program combines teen-friendly group therapy and family-based support to help teenagers with HIV manage mental health and stay on their HIV treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGraduate School of Public Health and Health Policy
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 19, 2025
Project endMay 31, 2030
Funding year2026
Award (this year)$1,064,042
NIH project number5R01MH140406-02
Project IDNIH-11417983 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents aged 15-19 living with HIV who may have depressive symptoms or adherence challenges.

Less likely to help

Adolescents without depressive symptoms or adherence issues may experience less direct benefit from the specific STREAMS components.

What this research studies

This project targets adolescents aged 15-19 living with HIV and tests a combined intervention that includes streamlined interpersonal psychotherapy groups and family-focused adherence counseling. It builds on prior pilot work showing feasibility of a brief depression screening and linkage to counseling, and it adapts successful adult/adolescent programs to a US and international context. The study will be implemented across 24 HIV clinics affiliated with ICHAD, evaluating how the integrated approach affects depression, adherence, and overall HIV care. If successful, STREAMS could offer a scalable model to improve mental health and treatment outcomes for ALWHIV.

Why it matters

Potential benefit: If successful, STREAMS could improve mood, boost ART adherence, and enhance overall health and quality of life for adolescents living with HIV.

How similar studies have gone: Prior feasibility and acceptability data from interventions like IPT-G and Suubi+Adherence support have shown promise, but the combination in ALWHIV is novel.

Where this research is happening

  • Graduate School of Public Health and Health Policy
    New York, United States
    Active

Researchers

  • Principal investigator: Kreniske, Philip — Graduate School of Public Health and Health Policy
  • Study coordinator: Kreniske, Philip

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.