Adolescent consent for HIV prevention in Rakai, Uganda

Improving understanding of Capacity to consent to sensitive biomedical HIV prevention Research among adolescents in Rakai Uganda (ICARE)

NIH-funded research Graduate School of Public Health and Health Policy · NIH-11471078

This project works with teens in Rakai, Uganda to find better ways for them to understand and give permission to take part in HIV prevention work and to learn about oral and injectable PrEP.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGraduate School of Public Health and Health Policy NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11471078 on NIH RePORTER

What this research studies

You'll be invited to join researchers through the Rakai Community Cohort Study to talk about how you understand giving permission for HIV-related work. They will compare how younger and older teens make decisions and try different ways of explaining consent to see which ones help you show understanding. The team will also check who would qualify for oral or injectable PrEP, ask about beliefs and interest in these prevention options, and collect information to guide future trials. At the end they will create a digital toolkit meant to help teens like you join HIV prevention efforts more easily and safely.

Who could benefit from this research

Good fit: Ideal candidates are adolescents and young adults in the Rakai region of Uganda, especially those around 12–18 years old who may be eligible for or interested in HIV prevention like PrEP.

Not a fit: People who live outside the Rakai area, older adults, or those not involved in HIV prevention efforts are unlikely to receive direct benefit from participating.

Why it matters

Potential benefit: If successful, this work could make it easier for adolescents to take part in HIV prevention research and access PrEP by reducing consent barriers and improving how information is presented.

How similar studies have performed: While PrEP has been highly effective in adults, using developmentally tailored consent approaches and digital toolkits for adolescents is relatively new and still being tested.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.