Strategies to improve HIV care for adolescents in Africa

Adaptive Strategies to Prevent and Treat Lapses of Retention in HIV Care for Adolescents (A4A)

NIH-funded research Washington University · NIH-10668384

This study is looking at ways to help young people aged 14-24 living with HIV in Africa by finding flexible support strategies that can adapt to their unique challenges, like stigma and access to care, so they can stay engaged in their treatment and improve their health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10668384 on NIH RePORTER

What this research studies

This research focuses on adolescents and young adults aged 14-24 living with HIV in Africa, who face unique challenges that lead to higher rates of treatment failure and mortality. The study aims to develop and test adaptive strategies that can effectively address the varying barriers these individuals encounter, such as social stigma and logistical issues. By starting with less intensive interventions and escalating support as needed, the research seeks to optimize resource use and improve engagement in HIV treatment. The approach is designed to be flexible and responsive to the individual needs of patients, ensuring that those who require more help receive it.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults aged 14-24 who are living with HIV in Africa.

Not a fit: Patients outside the age range of 14-24 or those not living with HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved retention in HIV care and better health outcomes for adolescents and young adults living with HIV.

How similar studies have performed: Previous research has shown that adaptive strategies can be effective in addressing complex health challenges, suggesting potential for success in this novel approach.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immuno-Deficiency SyndromeAcquired Immunologic Deficiency SyndromeAcquired Immunodeficiency SyndromeMental disorders
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.