NIH-funded research Career grant

Standardizing Antibiotic Prescribing for Children with Infections using New Metrics and Clinical Decision Tools

Official title: Standardizing Antibiotic Prescribing for Children Hospitalized with Infections using Novel Metrics and Electronic Clinical Decision Support Tools

Funded at Children's Mercy Hosp (Kansas City, Mo) · NIH-11414759 · Data updated 2026-11-12

A clinician-focused grant aims to improve how antibiotics are prescribed to hospitalized children by using new measures and an electronic decision support tool.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionChildren's Mercy Hosp (Kansas City, Mo)
NIH-funded
Lab location1 site (Kansas City, United States)
Project startSeptember 30, 2022
Project endSeptember 29, 2027
Funding year2026
Award (this year)$148,468
NIH project number5K08HS028845-05
Project IDNIH-11414759 on NIH RePORTER

Who could benefit from this research

Could help

Pediatric inpatients (0-11 years old) who require antibiotic treatment for infections.

Less likely to help

Children not receiving antibiotics or whose care does not involve inpatient antibiotic decisions may have little direct benefit.

What this research studies

This grant supports a career development effort to understand why frontline providers prescribe antibiotics differently and to make prescribing easier and more evidence-based on a pediatric inpatient unit. It focuses on how usability, workflow, and environment affect antibiotic choices, not just knowledge gaps. A mobile electronic clinical decision support tool will be tested to help prescribers follow guidelines in busy hospital settings. The project includes mentorship and a structured plan over several years to translate findings into practice.

Why it matters

Potential benefit: If successful, it could make antibiotic prescribing for hospitalized children more consistent with guidelines, reducing unnecessary use and improving patient safety.

How similar studies have gone: Previous work suggests decision support tools can improve guideline-concordant prescribing, but real-world usability in busy pediatric wards remains challenging and variable.

Where this research is happening

  • Children's Mercy Hosp (Kansas City, Mo)
    Kansas City, United States
    Active

Researchers

  • Principal investigator: Markham, Jessica Lynn — Children's Mercy Hosp (Kansas City, Mo)
  • Study coordinator: Markham, Jessica Lynn

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.