Smartphone-based mood and emotion monitoring for bipolar disorder

Detecting dynamic fluctuations in emotion, mood, and functioning: A digital phenotyping approach to clinical monitoring in bipolar disorder

NIH-funded research University of Michigan at Ann Arbor · NIH-11231253

This project uses an Android app that passively tracks voice and behavior to spot mood and emotion changes in people with bipolar disorder.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11231253 on NIH RePORTER

What this research studies

You would use the PRIORI Android app for six months while it passively samples ambient audio about every 15 minutes and generates emotion estimates. The app's machine learning algorithms turn audio and phone-sensor data into measures of emotional valence and arousal that the team compares with brief mood surveys. The goal is to reduce frequent, burdensome mood surveys by improving passive monitoring that works quietly in the background. About 160 people with known patterns of mood instability from an existing cohort will take part in this continuous digital monitoring protocol.

Who could benefit from this research

Good fit: Adults with bipolar disorder who have a history of mood instability, are willing to use an Android smartphone app, and agree to passive audio monitoring for about six months are ideal candidates.

Not a fit: People without bipolar disorder, those unwilling to share audio or use an Android phone, or those with consistently stable mood patterns may not benefit from this approach.

Why it matters

Potential benefit: If successful, this could help detect mood shifts earlier and make ongoing monitoring less burdensome for people with bipolar disorder.

How similar studies have performed: Earlier pilot work with the PRIORI app and other passive-sensing studies found links between audio features and mood, but larger and longer-term validation is still needed.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bipolar Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.