NIH-funded research R01 grant

Small, durable heart pump for children

Official title: Development of a Small, Durable, Hemocompatible Centrifugal Blood Pump for Children

Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11397585 · Data updated 2026-11-12

A child-friendly, compact heart pump is being developed and tested to help kids with severe heart failure while waiting for a donor heart.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State Univ Hershey Med Ctr
NIH-funded
Lab location1 site (Hershey, United States)
Project startSeptember 1, 2025
Project endJune 30, 2029
Funding year2026
Award (this year)$791,705
NIH project number5R01HL176797-02
Project IDNIH-11397585 on NIH RePORTER

Who could benefit from this research

Could help

Children with severe heart failure who are potential candidates for VAD support and transplant.

Less likely to help

Children outside the 10–35 kg weight range or without a potential for VAD-supported transplant may not benefit.

What this research studies

This grant aims to refine a small centrifugal blood pump (the PSU Child VAD) designed for children weighing roughly 10–35 kg. Researchers will conduct 30-day in-vivo tests and iterative design updates to ensure the device is safe, durable, and compatible with pediatric physiology. The project builds on prior animal testing and focuses on achieving reliable blood flow with minimal blood trauma and no organ damage.

Why it matters

Potential benefit: If successful, this device could provide safer long-term support for children awaiting transplant.

How similar studies have gone: Earlier animal studies showed promising biocompatibility and no end-organ failure, supporting feasibility.

Where this research is happening

  • Pennsylvania State Univ Hershey Med Ctr
    Hershey, United States
    Active

Researchers

  • Principal investigator: Jhun, Choon-Sik — Pennsylvania State Univ Hershey Med Ctr
  • Study coordinator: Jhun, Choon-Sik

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.