Sleep restriction study in children of hypertensive parents
Official title: Effects of Experimental Sleep Restriction in Offspring of Hypertensive Parents
Funded at Mayo Clinic Rochester · NIH-11321536 · Data updated 2026-11-12
A short-term study tests how limiting sleep affects blood pressure and heart health in adults who have a parent with hypertension.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $729,103 |
| NIH project number | 5R01HL169320-03 |
| Project ID | NIH-11321536 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults 21+ with or without a parental history of hypertension who can stay inpatient for a 10-day period.
✕Less likely to help
Individuals unable to participate in inpatient sleep protocols or without a parental history of hypertension may not benefit from the findings.
What this research studies
This study will recruit adults who either have a parent with hypertension or do not, and place them on controlled sleep schedules in a hospital setting for 10 days. Researchers will measure blood pressure and cardiovascular function to see if sleep loss worsens risk factors differently in the two groups. It’s a crossover design, so each participant experiences both sleep restriction and normal sleep periods. The goal is to understand how sleep habits might contribute to cardiovascular risk for people with a family history of hypertension.
Why it matters
Potential benefit: If successful, findings could inform personalized sleep guidelines to reduce cardiovascular risk in people with a family history of hypertension.
How similar studies have gone: Previous research shows sleep affects blood pressure, but this exact parental-history stratified sleep study is novel in its design.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Covassin, Naima — Mayo Clinic Rochester
- Study coordinator: Covassin, Naima
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.