Single-Cell Genomics Core for advanced human disease research
Official title: Single Cell Genomics Core
Funded at Dartmouth College · NIH-11406061 · Data updated 2026-11-12
A high-tech core grants researchers access to single-cell and spatial omics tools to study autoimmune diseases and other conditions, helping scientists understand disease at the cellular level.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | August 1, 2019 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $309,189 |
| NIH project number | 5P20GM130454-08 |
| Project ID | NIH-11406061 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with autoimmune conditions whose samples or data will be analyzed or whose disease biology will be studied through single-cell approaches.
✕Less likely to help
Patients not contributing samples or data to autoimmune-related research or not involved in studies using single-cell technologies may see no direct benefit.
What this research studies
This grant funds a centralized facility that provides state-of-the-art single-cell and spatial omics capabilities to Dartmouth researchers and regional partners. The core supports high-throughput data generation and rigorous computational analysis to reveal cellular changes and molecular pathways in diseases such as autoimmunity. By offering instrumentation, expert consultation, and methods development, the core accelerates discovery that could translate into better diagnostics and therapies. Researchers with this core can advance projects that involve patient samples, animal models, and translational studies across human health.
Why it matters
Potential benefit: If successful, patients could benefit from faster discoveries of disease mechanisms and more precise biomarkers or targets for autoimmune diseases.
How similar studies have gone: Previous use of single-cell and spatial-omics approaches has yielded impactful biological insights and publications, indicating promise for this line of work.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Kolling Iv, Fred W — Dartmouth College
- Study coordinator: Kolling Iv, Fred W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.