Single blood test to find many cancers early

Multi-Cancer Early Detection and Screening (MED SCREEN) Study

NIH-funded research Kaiser Foundation Research Institute · NIH-11252884

This project offers adults 45–70 a one-time blood test that looks for signs of many different cancers to help find them earlier than usual care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project IDNIH-11252884 on NIH RePORTER

What this research studies

You would be invited to give a single blood sample that is tested for signals of multiple cancers using cell-free DNA and other biological markers, then followed through your regular Kaiser Permanente care. The project will start at 21 Kaiser medical centers in California and may expand to more sites, using electronic health records to track results, referrals, diagnoses, treatments, and outcomes. Study staff will link the blood-test findings with routine screening and any follow-up tests or procedures you receive. The goal is to learn how acceptable and practical this blood approach is across real-world medical centers.

Who could benefit from this research

Good fit: Adults aged about 45 to 70 who receive care at participating Kaiser Permanente medical centers and are eligible for routine cancer screening are ideal candidates.

Not a fit: People younger than 45 or older than 70, those already diagnosed with cancer, or those who do not receive care at the participating Kaiser centers are unlikely to be eligible or benefit from this project.

Why it matters

Potential benefit: If successful, the blood test could help find cancers earlier, which may lead to earlier treatment and better outcomes for patients.

How similar studies have performed: Commercial multi-cancer blood tests exist and early data are promising, but large multicenter screening studies like this are still limited and relatively new.

Where this research is happening

Oakland, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.