Sex differences in what makes PTSD-like symptoms show up
Official title: Sex differences in susceptibility to a PTSD-like phenotype
Funded at Charlie Norwood VA Medical Center · NIH-11314507 · Data updated 2026-11-12
This grant explores why men and women may develop PTSD-like symptoms differently after trauma, using animal models to uncover gender-specific susceptibility factors.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Charlie Norwood VA Medical Center NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project start | April 1, 2018 |
| Project end | April 30, 2028 |
| Funding year | 2026 |
| NIH project number | 5I01BX003890-07 |
| Project ID | NIH-11314507 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals who may be at risk for PTSD due to exposure to traumatic experiences or those interested in translational research on susceptibility factors.
✕Less likely to help
Individuals not involved in trauma exposure research or those seeking immediate clinical treatment for PTSD may not directly benefit.
What this research studies
Researchers will study how sex differences influence the likelihood of developing PTSD-like traits after emotional trauma, using an established animal model. They aim to identify biological factors in the brain that differ between male and female subjects, guiding future approaches to prevention and treatment. The work focuses on susceptibility factors that could be identified or altered before trauma to reduce the risk of PTSD, with a special emphasis on differences in how males and females respond to potential resilience-building strategies.
Why it matters
Potential benefit: Insights from this work could inform gender-specific prevention and treatment approaches for PTSD.
How similar studies have gone: Previous animal studies have shown that sex can influence PTSD-like susceptibility, supporting potential applicability to humans.
Where this research is happening
-
Charlie Norwood VA Medical Center
Augusta, United States Active
Researchers
- Principal investigator: Vazdarjanova, Almira — Charlie Norwood VA Medical Center
- Study coordinator: Vazdarjanova, Almira
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.