Sequencing Core supports study of immune cells in lung infections
Official title: Sequencing Core
Funded at La Jolla Institute for Immunology · NIH-11398854 · Data updated 2026-11-12
A core sequencing grant helps researchers profile immune cells from people with lung infections to understand how T cells respond.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | June 15, 2015 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $328,279 |
| NIH project number | 5U19AI118626-12 |
| Project ID | NIH-11398854 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with lung infections or vaccination history relevant to SARS-CoV-2 or tuberculosis who donate samples for immune profiling.
✕Less likely to help
If a patient’s samples aren’t used for these specific immune profiling assays, they may not directly benefit.
What this research studies
The Sequencing Core provides high-throughput sequencing services to define molecular profiles of T cell subsets in the lungs of people exposed to pathogens like SARS-CoV-2 and TB. It offers bulk and single-cell RNA sequencing, TCR sequencing, and single-cell ATAC-seq to map gene expression, immune receptors, and chromatin accessibility. The core works with three projects, handling sample processing, library preparation, and data generation to ensure reproducible results for researchers studying human immune responses. This is a shared resource that could enable translational work toward better vaccines and therapies for lung infections.
Why it matters
Potential benefit: It could accelerate discovery of immune biomarkers and help develop targeted interventions for lung infections.
How similar studies have gone: Previous projects using similar sequencing approaches have successfully mapped immune cell states and TCR repertoires, supporting this strategy.
Where this research is happening
-
La Jolla Institute for Immunology
La Jolla, United States Active
Researchers
- Principal investigator: Seumois, Gregory — La Jolla Institute for Immunology
- Study coordinator: Seumois, Gregory
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.