SelfWrap: a dissolvable wrap to improve dialysis fistula outcomes
Official title: Process Validation and Commercialization of SelfWrap, a Bioabsorbable Wrap to Improve Dialysis Access Outcomes
Funded at Venostent, INC. · NIH-11316739 · Data updated 2026-11-12
A new bioabsorbable wrap called SelfWrap is being developed to help arteriovenous fistulas used for hemodialysis last longer and work better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Venostent, INC. NIH-funded |
| Lab location | 1 site (Houston, UNITED STATES) |
| Project start | September 15, 2026 |
| Project end | September 14, 2027 |
| Funding year | 2026 |
| Award (this year) | $500,000 |
| NIH project number | 1SB1HL184448-01 |
| Project ID | NIH-11316739 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients undergoing AV fistula creation or those at high risk of fistula failure due to vein weakness and neointimal hyperplasia may benefit.
✕Less likely to help
Patients with non-AV fistula access options or those not requiring dialysis may not directly benefit.
What this research studies
This project aims to validate and commercialize a bioabsorbable wrap applied during AV fistula creation to reduce failure and abandonment rates. It focuses on protecting the vein–artery connection by minimizing vessel injury and neointimal hyperplasia that lead to occlusion. The work includes translational steps toward bringing SelfWrap to clinical use, with an emphasis on manufacturing and practical deployment. If successful, it could mean more patients have durable access for life-sustaining hemodialysis with fewer procedures.
Why it matters
Potential benefit: If successful, patients could experience longer-lasting AV fistulas and fewer dialysis-access failures, reducing surgeries and complications.
How similar studies have gone: Prior approaches to prevent venous failure in AV access have shown mixed results; this project is advancing a novel, potentially more effective wrap.
Where this research is happening
-
Venostent, INC.
Houston, United States Active
Researchers
- Principal investigator: Boire, Timothy Charles — Venostent, INC.
- Study coordinator: Boire, Timothy Charles
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.