Screening women with lower genital tract cancers for anal cancer precursors
The effectiveness of screening women with lower genital tract neoplasia or cancers for anal cancer precursors
This study is looking at how well screening for early signs of anal cancer works for women over 50 who have had certain lower genital tract issues, to see if it can help catch problems early and improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10914069 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of screening women who have had lower genital tract neoplasia or cancers for precursors to anal cancer. The study focuses on women aged 50 and older, who are at a higher risk for developing these precursors. It aims to evaluate the benefits and potential harms of screening methods, such as cytologic and HPV testing, which may even be performed by patients themselves. By identifying precancerous anal lesions early, the research seeks to improve outcomes for this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are women aged 50 and older who have a history of lower genital tract dysplasia or cancer.
Not a fit: Patients who do not have a history of lower genital tract cancers or dysplasia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and prevention of anal cancer in women at high risk.
How similar studies have performed: Previous research has shown promising results in screening for anal cancer precursors in similar high-risk populations, indicating that this approach may be effective.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Sigel, Keith Magnus — Icahn School of Medicine at Mount Sinai
- Study coordinator: Sigel, Keith Magnus
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.