Screening new compounds for mental health treatments and brain imaging.
Official title: TO AWARD THE BASE PERIOD FOR NIMH PSYCHOACTIVE DRUG SCREENING PROGRAM (PDSP). BASE POP: 08/30/2023-08/29/2024.
Funded at Univ of North Carolina Chapel Hill · NIH-11180021 · Data updated 2026-11-12
This study is looking for new medicines made from both natural and synthetic ingredients that could help improve treatments for mental health issues, using advanced brain imaging to see how they work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 30, 2023 |
| Project end | August 29, 2025 |
| Funding year | 2024 |
| Award (this year) | $3,140,878 |
| NIH project number | 75N95023C00021-P00001-9999-1 |
| Project ID | NIH-11180021 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from various mental health disorders who may benefit from new therapeutic options.
✕Less likely to help
Patients with well-established treatment plans that are already effective for their conditions may not receive additional benefits from this research.
What this research studies
This research focuses on screening both synthetic and natural compounds to identify potential new treatments for mental health disorders. It aims to develop these compounds as tools for basic and clinical research, as well as for use in advanced brain imaging techniques like PET and fMRI. Patients may benefit from the identification of new therapeutic agents that could improve treatment options for various psychiatric conditions. The research employs advanced imaging technologies to better understand how these compounds interact with the brain.
Why it matters
Potential benefit: If successful, this research could lead to new and effective treatments for mental health disorders.
How similar studies have gone: Previous research has shown promise in using similar approaches to develop new treatments and imaging techniques for mental health disorders.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Roth, Bryan — Univ of North Carolina Chapel Hill
- Study coordinator: Roth, Bryan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.