Risk profile to identify cerebral visual impairment in children
Official title: Establishing a risk-profile for Cerebral Visual Impairment
Funded at Massachusetts General Hospital · NIH-11453237 · Data updated 2026-11-12
A pediatric-focused study will use existing medical records to identify risk factors and protective factors for cerebral visual impairment to help doctors screen at-risk infants earlier.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $453,750 |
| NIH project number | 1R21EY038227-01A1 |
| Project ID | NIH-11453237 on NIH RePORTER |
Who could benefit from this research
✓Could help
Infants and young children who have or are at risk of CVI or related brain injury, and their families.
✕Less likely to help
Children without risk factors or CVI are unlikely to benefit from this risk profiling.
What this research studies
This project uses a large, already-collected clinical dataset to find patterns that predict which infants are at higher or lower risk of CVI. It will apply elastic net regression to balance many infant, maternal, and neurological factors and create a practical risk profile. The goal is to enable timely screening and targeted interventions so at-risk children can receive needed support.
Why it matters
Potential benefit: If successful, the findings could lead to earlier CVI screening and better outcomes for children at risk.
How similar studies have gone: Previous work has shown that risk profiling can help identify at-risk groups in pediatric neuro-ophthalmology, but this project uses a large dataset to refine predictors for CVI.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Bauer, Corinna M — Massachusetts General Hospital
- Study coordinator: Bauer, Corinna M
Related research
Other NIH-funded projects on the same topics.
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Understanding why prematurity affects vision and how to prevent it
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Cerebral Visual Impairment: a new bedside-friendly eye-tracking plus neuropsychology test kit
A small study will combine quick brain-based visual tests with mobile eye tracking to better diagnose cerebral visual impairment in children.
-
Higher-level vision problems in cerebral visual impairment
This project looks at why people with cerebral visual impairment (CVI) have trouble finding objects, navigating busy scenes, and using vision to guide movement.
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Understanding how ableism affects the health of children with visual impairments
This study looks at how negative attitudes and barriers in society affect the health of children who are blind or visually impaired, especially those from underrepresented communities, and it aims to understand their experiences to help improve their well-being.
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Understanding Vision Problems in Premature Babies
This project aims to understand why premature babies often develop vision problems and nearsightedness.
-
Using eye tracking to understand visual impairment in children
This study is looking at how eye tracking can help us understand how kids with cortical visual impairment see things, so we can learn more about their vision and find better ways to help them.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.