Resource Development Core for Pig Models to Study Airborne Flu Transmission
Official title: Research Development Core
Funded at University of Missouri-Columbia · NIH-11451503 · Data updated 2026-11-12
A research program will develop and provide pig models, including genetically engineered pigs, to study how pre-existing immunity and the environment affect airborne influenza transmission.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri-Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project start | September 1, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $241,561 |
| NIH project number | 1P01AI202802-01 |
| Project ID | NIH-11451503 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are patients or communities at risk for influenza during outbreaks where improved vaccines or transmission-reducing measures could help.
✕Less likely to help
Individuals not participating in related human studies could still benefit indirectly from improved prevention strategies.
What this research studies
This grant supports Core B to produce and maintain wild-type and genetically engineered pigs used in Projects 1 and 2 to understand how antibodies and T cells influence flu transmission. It highlights pig models as a bridge to human biology due to similarities in anatomy and immune responses. The work focuses on how humoral and cellular immunity shape viral clearance, shedding, and spread through airborne routes.
Why it matters
Potential benefit: If successful, this work could lead to better vaccines and strategies to prevent airborne influenza transmission in humans.
How similar studies have gone: Preclinical pig models have shown promise in translating influenza transmission findings to humans, supporting this translational approach.
Where this research is happening
-
University of Missouri-Columbia
Columbia, United States Active
Researchers
- Principal investigator: Lee, Kiho — University of Missouri-Columbia
- Study coordinator: Lee, Kiho
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.