NIH-funded research R21 grant

Regulatory ideas to help young adults quit vaping in a simulated vape shop

Official title: Regulatory Strategies for Promoting Cessation in a Simulated Experimental Tobacco Retail Lab Space

Funded at University of Southern California · NIH-11464595 · Data updated 2026-11-12

This project tests two policy ideas in a realistic fake vape shop to see if easier access to quitting aids and visible stop-smoking resources help young adults who want to quit vaping.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California
NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project startJuly 6, 2026
Project endJune 30, 2028
Funding year2026
Award (this year)$426,828
NIH project number1R21CA318548-01
Project IDNIH-11464595 on NIH RePORTER

Who could benefit from this research

Could help

Young adults who vape and are interested in quitting.

Less likely to help

Individuals without interest in quitting or not exposed to the simulated environment may not benefit.

What this research studies

Researchers will use a state-of-the-art simulated vape shop called The Puff Point to test how two policies affect young adults’ vaping purchase decisions and their intentions to quit. They will examine whether providing nicotine replacement therapies and displaying cessation resources at the point of sale changes behavior in a controlled, lab-like setting. The study uses a 2x2 factorial design to separately and jointly evaluate these interventions. Results could inform real-world retail policies aimed at supporting quit attempts among young people who vape.

Why it matters

Potential benefit: If successful, the interventions could guide regulations that make quitting aids more accessible and improve visibility of cessation resources for young vapers.

How similar studies have gone: Previous lab-based demonstrations suggest policy changes at the point of sale can influence cessation-related behaviors, but real-world effectiveness requires further study.

Where this research is happening

  • University of Southern California
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Barrington-Trimis, Jessica Louise — University of Southern California
  • Study coordinator: Barrington-Trimis, Jessica Louise

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.