Reducing the risk of depression recurrence in adolescents
Developing rumination-focused treatment to reduce risk for depression recurrence (RDR) in adolescence
['FUNDING_OTHER'] · OHIO STATE UNIVERSITY · NIH-10924030
This study is testing a new way to help teens aged 14-18 who have had depression learn to think differently about their problems, so they can feel better and avoid getting depressed again.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OHIO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (Columbus, UNITED STATES) |
| Trial ID | NIH-10924030 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a treatment aimed at helping adolescents aged 14-18 who have experienced Major Depressive Disorder (MDD) to prevent future episodes of depression. The approach involves teaching participants to shift from ruminative thinking patterns, which can exacerbate depression, to more adaptive problem-solving and emotional processing strategies. By utilizing a specific type of cognitive behavioral therapy called rumination-focused cognitive behavioral therapy (RFCBT), the study aims to modify the way adolescents think about their difficulties and emotions. The research will involve measuring changes in brain connectivity related to these thinking patterns to assess the effectiveness of the treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 14-18 who have experienced a previous episode of Major Depressive Disorder but are currently in remission.
Not a fit: Patients who have not experienced Major Depressive Disorder or those outside the age range of 14-18 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the likelihood of depression recurrence in adolescents, leading to improved mental health outcomes.
How similar studies have performed: Initial studies have shown promise in using similar cognitive behavioral approaches to reduce rumination and improve mental health outcomes in both adolescents and adults.
Where this research is happening
Columbus, UNITED STATES
- OHIO STATE UNIVERSITY — Columbus, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LANGENECKER, SCOTT A — OHIO STATE UNIVERSITY
- Study coordinator: LANGENECKER, SCOTT A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anxiety Disorders