Reaching and re-engaging people who stopped HIV care in Zambia

Sequential Strategies to Reach and Reengage Individuals after Lapses from HIV Care in Zambia

NIH-funded research Washington University · NIH-11386470

This project tries a stepwise approach—personalized outreach plus community medication delivery—to help people in Zambia who stopped HIV care restart treatment and stay on it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11386470 on NIH RePORTER

What this research studies

If you've missed HIV appointments or stopped taking treatment, this project will try to bring you back into care and then help you stay on treatment. The team will use navigators who tailor outreach, care coordination, and psychosocial support to each person's barriers. They will combine that with community-based medication delivery so drugs are easier to get without repeated clinic visits. The work compares different sequences and combinations of these approaches to find ways that keep people engaged long-term.

Who could benefit from this research

Good fit: Adults living with HIV in Zambia who have missed appointments or stopped antiretroviral therapy and can be reached by clinic or community outreach.

Not a fit: People who have never interrupted care, live outside the study's catchment areas, or cannot be located by outreach teams are unlikely to benefit directly.

Why it matters

Potential benefit: Could help people who lapse from HIV care restart ART faster and stay on it, lowering viral levels and reducing illness and hospitalizations.

How similar studies have performed: Navigation and community medication-delivery programs have shown promise for people starting or stable on ART, but combining and timing these interventions specifically after treatment lapses is relatively untested.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusChronic Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.