NIH-funded research Sbir 1 grant

Quality assurance phantom for lung hyperpolarized xenon MRI

Official title: Quality assurance imaging phantom for clinical pulmonary gas exchange xenon MRI

Funded at Spinhance, LLC · NIH-11316661 · Data updated 2026-11-12

A new 3D-printed phantom will help doctors and researchers test and standardize HP 129Xe lung MRI to better study how lungs transfer gas into the blood.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionSpinhance, LLC
NIH-funded
Lab location1 site (Rydal, UNITED STATES)
Project startSeptember 15, 2026
Project endSeptember 14, 2027
Funding year2026
Award (this year)$306,358
NIH project number1R43EB038849-01
Project IDNIH-11316661 on NIH RePORTER

Who could benefit from this research

Could help

Clinicians and researchers using HP 129Xe MRI for lung function assessment.

Less likely to help

Patients not undergoing HP 129Xe MRI imaging or related phantom validation may not directly benefit.

What this research studies

This project builds a pressurized xenon phantom with 3D-printed structures to mimic lung tissue and gas exchange. It will qualify and evaluate how well HP 129Xe MRI can measure gas exchange in the lung. The work aims to support multi-site trials and help clinics adopt this imaging technology with reliable, comparable results.

Why it matters

Potential benefit: If successful, the phantom could improve consistency and accuracy of HP 129Xe lung MRI across sites, aiding faster clinical adoption.

How similar studies have gone: HP 129Xe MRI has demonstrated promise, but standardized phantoms are needed for multi-site consistency.

Where this research is happening

  • Spinhance, LLC
    Rydal, United States
    Active

Researchers

  • Principal investigator: Drachman, Nicholas — Spinhance, LLC
  • Study coordinator: Drachman, Nicholas

Related research

Other NIH-funded projects on the same topics.

  • A new imaging system for lung function using a special gas

    This study is testing a new imaging device that uses a special gas to take real-time pictures of your lungs during MRI scans, so you won’t have to hold your breath, making it easier for everyone, no matter their age or health.

    NIH research Spinhance, LLC · Rydal, UNITED STATES · NIH-11070224

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.