A new imaging system for lung function using a special gas

Free-Breathing Dynamic Cardiopulmonary Function Imaging System to use with Xenon MRI

NIH-funded research Spinhance, LLC · NIH-11070224

This study is testing a new imaging device that uses a special gas to take real-time pictures of your lungs during MRI scans, so you won’t have to hold your breath, making it easier for everyone, no matter their age or health.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionSpinhance, LLC NIH-funded
Lab location1 site (Rydal, UNITED STATES)
Project IDNIH-11070224 on NIH RePORTER

What this research studies

This research focuses on developing a novel imaging device that uses Hyperpolarized Xenon-129 gas to continuously monitor lung function during MRI scans. The device aims to provide real-time imaging without requiring patients to hold their breath, making it accessible for individuals of all ages and health conditions. By integrating physiological monitoring, the system will capture dynamic changes in airflow and blood flow, enhancing the accuracy of lung imaging. This innovative approach seeks to eliminate biases associated with traditional imaging methods and improve the overall quality of lung assessments.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with respiratory conditions, those requiring lung function assessments, and patients of any age who may benefit from improved imaging techniques.

Not a fit: Patients who do not have any lung-related issues or those who are unable to undergo MRI due to contraindications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and accessible lung function assessments for patients, improving diagnosis and treatment planning.

How similar studies have performed: While the use of Hyperpolarized Xenon-129 in imaging has been explored in small-animal studies, this specific application in human lung imaging represents a novel approach.

Where this research is happening

Rydal, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.