Psychiatric genomics to understand and translate bipolar disorder biology
Official title: Psychiatric Genomics Consortium: Mechanisms and Translation
Funded at Univ of North Carolina Chapel Hill · NIH-11566449 · Data updated 2026-11-12
A large genetics project is studying how inherited DNA differences influence bipolar disorder and how this knowledge could lead to better care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 1, 2026 |
| Project end | July 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $156,922 |
| NIH project number | 3R01MH142618-01S5 |
| Project ID | NIH-11566449 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with bipolar disorder or related psychiatric conditions who may participate in future genetic studies or receive insights from new research developments.
✕Less likely to help
People without bipolar disorder or related conditions may not directly benefit from this specific genetic research.
What this research studies
This grant supports a big collaboration to analyze how genetic factors contribute to bipolar disorder and related conditions. Researchers will combine many datasets, use advanced methods to map genetic variants, and explore how these findings relate to biology and health. The work aims to connect basic genetic discoveries to potential clinical insights and improve understanding of mechanisms, risk, and resilience. The project also emphasizes training and outreach so clinicians and researchers can use genetic information more effectively in care.
Why it matters
Potential benefit: If successful, findings could improve understanding of bipolar disorder biology and inform future treatments and risk prediction.
How similar studies have gone: Previous large-scale psychiatric genetics efforts have yielded numerous genetic associations and mechanistic leads, with ongoing translation to clinical context.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Sullivan, Patrick F — Univ of North Carolina Chapel Hill
- Study coordinator: Sullivan, Patrick F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.