Protecting the kidney and other organs after kidney injury
Official title: Protecting the kidney and remote organs following renal ischemia
Funded at Rlr VA Medical Center · NIH-11109618 · Data updated 2026-11-12
This study is looking at ways to help protect the kidneys and other organs from damage caused by a serious condition called acute kidney injury, which affects many people in the hospital, and it’s exploring new treatments that could improve recovery and health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rlr VA Medical Center NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | April 1, 2022 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01BX005346-04 |
| Project ID | NIH-11109618 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults over 21 who are hospitalized and at risk of or experiencing acute kidney injury.
✕Less likely to help
Patients with chronic kidney disease who are not currently experiencing acute kidney injury may not benefit from this research.
What this research studies
This research investigates how to protect the kidneys and other organs from damage caused by ischemic acute kidney injury (AKI), which is a serious condition affecting many hospitalized patients. The study focuses on understanding the inflammatory responses and organ dysfunction that occur after kidney injury, and explores the use of adult-cell based therapies and extracellular vesicles as potential treatments. By examining the communication between the injured kidneys and other organs, the research aims to develop effective therapies to improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce mortality and improve recovery for patients suffering from acute kidney injury.
How similar studies have gone: Previous research has shown promise in using cell-based therapies for kidney injury, indicating that this approach may be effective.
Where this research is happening
-
Rlr VA Medical Center
Indianapolis, United States Active
Researchers
- Principal investigator: Kelly, Katherine J — Rlr VA Medical Center
- Study coordinator: Kelly, Katherine J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.