Preventing thinking problems and repeat stroke after a brain bleed by improving blood pressure and addressing racial/ethnic gaps
Official title: Race / Ethncicity, Hypertension and Prevention of VCID and Stroke after Intracerebral Hemmorrhage
Funded at Massachusetts General Hospital · NIH-11145781 · Data updated 2026-11-12
This project tests ways to help people who survived a brain bleed (intracerebral hemorrhage) keep their blood pressure under control to lower the chance of vascular cognitive decline or another stroke, with attention to racial and ethnic differences.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | February 1, 2016 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $2,004,572 |
| NIH project number | 5R01NS093870-09 |
| Project ID | NIH-11145781 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults who have survived an intracerebral hemorrhage and have high or unstable blood pressure, particularly people from diverse racial and ethnic backgrounds.
✕Less likely to help
People without a prior intracerebral hemorrhage or without hypertension are unlikely to be included or to directly benefit from this project.
What this research studies
As a survivor of intracerebral hemorrhage, this project follows patients like me to see how high blood pressure and everyday social factors affect thinking problems (VCID) and the risk of another stroke. The team will collect blood pressure measurements, medical-record data, and information about non-medical drivers of health (such as housing, access to care, and social support) and track outcomes over time. Researchers will look for differences by race and ethnicity to understand why some groups have worse blood pressure control and outcomes. The results will be used to design future programs aimed at better engaging patients and improving blood pressure after ICH.
Why it matters
Potential benefit: If successful, this work could lead to programs that improve blood pressure control after ICH and reduce cognitive decline and recurrent stroke, especially for historically under-served racial and ethnic groups.
How similar studies have gone: Previous blood-pressure lowering trials after ICH have generally failed to improve outcomes because they struggled to engage patients, and systematic study of non-medical drivers of health in ICH is a relatively new approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Rosand, Jonathan — Massachusetts General Hospital
- Study coordinator: Rosand, Jonathan
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.