Preventing opioid use disorder in at-risk individuals

CTN-139 - Subthreshold Opioid Use Disorder Prevention (CoCare)

NIH-funded research Oregon Health & Science University · NIH-11295202

This study is all about helping people who might be at risk of developing problems with opioid use by offering them support, education, and resources to keep them healthy and prevent those issues from getting worse.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOregon Health & Science University NIH-funded
Lab location1 site (Portland, United States)
Project IDNIH-11295202 on NIH RePORTER

What this research studies

This research focuses on preventing the development of opioid use disorder in individuals who may be at risk. It employs a community-based approach to identify and support those with subthreshold symptoms of opioid use disorder, providing them with resources and interventions to reduce their risk. The program aims to engage participants through education, counseling, and support services tailored to their needs. By addressing the issue early, the research seeks to mitigate the potential progression to full-blown opioid use disorder.

Who could benefit from this research

Good fit: Ideal candidates for participation are individuals who exhibit early signs of opioid use disorder or are at risk due to various factors such as previous substance use or environmental influences.

Not a fit: Patients who are already diagnosed with opioid use disorder or those who do not exhibit any risk factors for developing the disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of opioid use disorder among at-risk populations.

How similar studies have performed: Previous research has shown that early intervention programs can effectively prevent the progression of substance use disorders, indicating a promising approach for this initiative.

Where this research is happening

Portland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions disease preventiondisorder preventionopiate use disorderopioid use disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.