Preventing infections from catheters using a special nitric oxide device
Prevention of catheter related infections via photoactive nitric oxide delivery device
This study is testing a new device that releases nitric oxide to help keep catheters safe by preventing infections and blood clots, making it better for patients who need these tubes for medical treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project ID | NIH-11080945 on NIH RePORTER |
What this research studies
This research focuses on developing a device that delivers nitric oxide to prevent infections and blood clots associated with intravascular catheters. Catheters are commonly used in medical settings but can become contaminated, leading to serious infections and complications. The study aims to create a polymer-based device that releases nitric oxide, which has been shown to inhibit bacterial growth and prevent platelet activation. By mimicking the natural protective mechanisms of blood vessels, this device could enhance the safety and effectiveness of catheter use in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who require the use of intravascular catheters, particularly those at high risk for infections.
Not a fit: Patients who do not require catheterization or have contraindications for catheter use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of catheter-related infections and improve patient outcomes.
How similar studies have performed: Previous research has shown promising results with nitric oxide delivery systems in preventing infections and thrombosis, indicating a potential for success with this approach.
Where this research is happening
Athens, United States
- University of Georgia — Athens, United States (Active)
Researchers
- Principal investigator: Brisbois, Elizabeth Joy — University of Georgia
- Study coordinator: Brisbois, Elizabeth Joy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.