Preventing infections from catheters using a special nitric oxide device
Official title: Prevention of catheter related infections via photoactive nitric oxide delivery device
Funded at University of Georgia · NIH-11080945 · Data updated 2026-11-12
This study is testing a new device that releases nitric oxide to help keep catheters safe by preventing infections and blood clots, making it better for patients who need these tubes for medical treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | August 1, 2023 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $475,865 |
| NIH project number | 5R01HL170574-03 |
| Project ID | NIH-11080945 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who require the use of intravascular catheters, particularly those at high risk for infections.
✕Less likely to help
Patients who do not require catheterization or have contraindications for catheter use may not benefit from this research.
What this research studies
This research focuses on developing a device that delivers nitric oxide to prevent infections and blood clots associated with intravascular catheters. Catheters are commonly used in medical settings but can become contaminated, leading to serious infections and complications. The study aims to create a polymer-based device that releases nitric oxide, which has been shown to inhibit bacterial growth and prevent platelet activation. By mimicking the natural protective mechanisms of blood vessels, this device could enhance the safety and effectiveness of catheter use in patients.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of catheter-related infections and improve patient outcomes.
How similar studies have gone: Previous research has shown promising results with nitric oxide delivery systems in preventing infections and thrombosis, indicating a potential for success with this approach.
Where this research is happening
-
University of Georgia
Athens, United States Active
Researchers
- Principal investigator: Brisbois, Elizabeth Joy — University of Georgia
- Study coordinator: Brisbois, Elizabeth Joy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.