Preventing heart disease in patients with lupus nephritis
Early and Personalized Cardiovascular Disease Preventive Care in Lupus Nephritis (EPiC-LN)
This study is looking to find better ways to prevent heart disease in Black patients with lupus nephritis, especially focusing on who might benefit most from certain treatments and how to make those treatments safer, particularly for young women who are pregnant.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10949235 on NIH RePORTER |
What this research studies
This research focuses on improving cardiovascular disease prevention in patients with lupus nephritis, particularly among Black patients who are at higher risk. It aims to identify which patients are most likely to benefit from preventive therapies and how to tailor these treatments to individual risk factors. The project will also address concerns about the safety and efficacy of these therapies, especially for young women during pregnancy. By developing an implementation guide for clinicians, the research seeks to enhance decision-making and support the use of effective therapies to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with lupus nephritis, particularly those who are Black and at risk for cardiovascular disease.
Not a fit: Patients without lupus nephritis or those who do not have risk factors for cardiovascular disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of cardiovascular disease and improve survival rates for patients with lupus nephritis.
How similar studies have performed: Previous research has shown promising results in improving cardiovascular disease prevention strategies in similar patient populations, indicating that this approach has potential for success.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Garg, Shivani — University of Wisconsin-Madison
- Study coordinator: Garg, Shivani
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.