Preventing anal cancer in men who have sex with men living with HIV
Integrated Model for the Prevention of Anal Cancer using screen and Treat for HSIL (IMPACT)
This study is looking to help men who have sex with men and are living with HIV by offering a program to screen and treat early signs of anal cancer, making it easier for them to get the care they need in Nigeria and the U.S.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10907554 on NIH RePORTER |
What this research studies
This research focuses on preventing anal cancer among men who have sex with men (MSM) living with HIV by implementing a screening and treatment program for high-grade squamous intraepithelial lesions (HSIL). The study will take place at the TRUST clinic in Nigeria, leveraging existing HIV care infrastructure to enhance access to anal cancer prevention interventions. By addressing knowledge gaps and barriers to treatment, the project aims to increase the uptake of HSIL screening and treatment in this high-risk population. Participants will be involved in a randomized controlled trial across multiple clinical sites in the United States and Nigeria.
Who could benefit from this research
Good fit: Ideal candidates for this research are men who have sex with men and are living with HIV, particularly those in low- and middle-income countries.
Not a fit: Patients who do not identify as men who have sex with men or who are not living with HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of anal cancer in a vulnerable population.
How similar studies have performed: Previous studies have shown success in implementing HSIL screening and treatment in similar populations, indicating a promising approach.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Nowak, Rebecca G. — University of Maryland Baltimore
- Study coordinator: Nowak, Rebecca G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.