NIH-funded research R01 grant

Prenatal exercise modes and how they affect child obesity risk

Official title: Effect of exercise modality during pregnancy on childhood obesity risk

Funded at East Carolina University · NIH-11358394 · Data updated 2026-11-12

This study tests which exercise type during pregnancy best protects children from obesity and metabolic problems later in life for women who are overweight or obese.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEast Carolina University
NIH-funded
Lab location1 site (Greenville, United States)
Project startMay 15, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$662,267
NIH project number5R01DK129480-05
Project IDNIH-11358394 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pregnant women who are overweight or obese at conception or early in pregnancy and are able to participate in prescribed exercise programs.

Less likely to help

Pregnant individuals who cannot exercise due to medical reasons or who have contraindications to physical activity may not benefit.

What this research studies

If a pregnant woman is overweight or obese, her exercise choices might shape her child’s health for years to come. The study will compare different prenatal exercise modes to see which ones most improve health markers in both mother and baby, aiming to lower risks like obesity and metabolic syndrome in early childhood. It uses a randomized design with 284 pregnant participants to evaluate outcomes related to infant growth and metabolic health. Results could guide safe, effective exercise recommendations for at-risk pregnancies. The research is conducted at East Carolina University under the leadership of Dr. Linda E. May.

Why it matters

Potential benefit: If successful, the findings could lead to clear, actionable exercise guidelines for overweight or obese pregnant women to improve long-term health for their children.

How similar studies have gone: Prior work shows benefits of exercise during pregnancy, but this trial seeks to determine which mode provides the greatest advantages for both mother and child.

Where this research is happening

  • East Carolina University
    Greenville, United States
    Active

Researchers

  • Principal investigator: May, Linda E — East Carolina University
  • Study coordinator: May, Linda E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.