NIH-funded research NIH-funded research

Pregnancy-focused dialectical behavior skills to support two generations

Official title: Developing pregnancy-specific dialectical behavior therapy skills to promote multigenerational mental health

Funded at Duke University · NIH-11318875 · Data updated 2026-11-12

A new program tests whether teaching pregnant people emotion-regulation skills can improve the health and well‑being of both the mother and her baby, from pregnancy through early infancy.

More Pregnancy research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startApril 15, 2025
Project endMarch 31, 2027
Funding year2026
Award (this year)$1,349,756
NIH project number5R61MH138444-02
Project IDNIH-11318875 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant individuals experiencing emotion dysregulation who are in the care of Duke University and eligible for participation during the prenatal period.

Less likely to help

Participants without emotion dysregulation or those outside the prenatal period may not experience direct benefits.

What this research studies

This project combines a group skills approach based on dialectical behavior therapy to address emotion dysregulation during pregnancy. It aims to see if improving maternal emotion regulation can lead to better infant neurobehavior and self-regulation at birth and around six months old. The study is designed as an R61/R33 transition to test feasibility and early effects in pregnant individuals and their infants. Researchers will monitor maternal responses and infant outcomes to determine if this prenatal intervention can prevent later emotional and behavioral difficulties. The work builds on data suggesting prenatal emotion regulation affects maternal physiology and infant behavior, and seeks to translate that into a pregnancy‑focused preventive strategy.

Why it matters

Potential benefit: If successful, the approach could become a preventive intervention to promote healthier outcomes for both mothers and babies starting before birth.

How similar studies have gone: Prior research links prenatal emotion regulation to infant outcomes, but this project tests a novel, pregnancy‑focused group skills program.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Conradt, Liz D — Duke University
  • Study coordinator: Conradt, Liz D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.