Predicting therapy outcomes for anxiety and depression
An Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome in Anxiety and Depression
['FUNDING_R01'] · LAUREATE INSTITUTE FOR BRAIN RESEARCH · NIH-10886756
This study is looking at how different types of therapy can help people who are dealing with both anxiety and depression, and it will help figure out which therapy works best for you based on how you respond to different situations.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LAUREATE INSTITUTE FOR BRAIN RESEARCH (nih funded) |
| Locations | 1 site (TULSA, UNITED STATES) |
| Trial ID | NIH-10886756 on ClinicalTrials.gov |
What this research studies
This research investigates how different behavioral therapies can help individuals with anxiety and depression by using a computational framework to predict outcomes. Participants will be recruited who experience both anxiety and depression symptoms and will be randomly assigned to one of three therapy types: behavioral activation, exposure-based therapy, or supportive therapy. The goal is to understand which therapy is most effective based on individual responses to approach and avoidance behaviors. By analyzing neural and behavioral responses, the research aims to improve treatment strategies for these common mental health conditions.
Who could benefit from this research
Good fit: Ideal candidates are individuals experiencing both anxiety and depression symptoms who are seeking therapeutic intervention.
Not a fit: Patients who do not have symptoms of anxiety or depression may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients suffering from anxiety and depression.
How similar studies have performed: Previous research has shown promise in using behavioral therapies for anxiety and depression, but this approach of integrating computational predictions is relatively novel.
Where this research is happening
TULSA, UNITED STATES
- LAUREATE INSTITUTE FOR BRAIN RESEARCH — TULSA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: AUPPERLE, ROBIN L — LAUREATE INSTITUTE FOR BRAIN RESEARCH
- Study coordinator: AUPPERLE, ROBIN L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Affective Disorders, Anxiety Disorders