NIH-funded research R01 grant

Predicting and reducing donor drop-out among racial/ethnic minority kidney donors

Official title: Transforming Curiosity into Donation: Validating a Risk Prediction Index to Detect and Prevent Drop-Out in Potential Living Kidney Donors who are Racial/Ethnic Minorities

Funded at Methodist Hospital Research Institute · NIH-11383472 · Data updated 2026-11-12

A study to help people from minority backgrounds who are considering living kidney donation understand and reduce the risk of dropping out during donor screening.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMethodist Hospital Research Institute
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 1, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$239,255
NIH project number5R01DK137111-04
Project IDNIH-11383472 on NIH RePORTER

Who could benefit from this research

Could help

Adults from racial/ethnic minority groups considering living kidney donation who begin the donor evaluation process.

Less likely to help

Individuals not pursuing or considering living donation or those who are not in the donor evaluation pathway.

What this research studies

This project analyzes donor screening data to find early signs that someone might stop the donation process. It will create a risk index (LD-DROP) to identify individuals at higher risk of dropping out so centers can provide targeted support. The work uses existing donor databases to understand barriers and tailor outreach, aiming to improve access to living donor kidney transplantation for those with greater financial and healthcare challenges. The study involves secondary analyses of data and collaboration across regional and national donor programs.

Why it matters

Potential benefit: If successful, the index could help transplant programs support more potential donors to complete evaluation and increase access to living-donor kidney transplants.

How similar studies have gone: Prior research shows that risk prediction in donor evaluation is feasible and can guide targeted interventions, though this exact LD-DROP index is novel.

Where this research is happening

  • Methodist Hospital Research Institute
    Houston, United States
    Active

Researchers

  • Principal investigator: Waterman, Amy Doggette — Methodist Hospital Research Institute
  • Study coordinator: Waterman, Amy Doggette

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.